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      丛羽生   教授 分享到

      研究方向: 衰老生物学、细胞生物学
      成果数量: 7 条 ,属于本机构的个人成果 7 条 ,属于医学院数量为: 4
      超星被引量: 4   WOS被引量: 0   H指数: 1

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Zhenyu Ju

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Fan Yang

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Jinbiao Ma

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Xia Yi

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Xian Wang

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Zhou Songyang

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Wenbin Ma

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Yanlian Chen

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Daojun Diao

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Yuyang Tian

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检索结果: 返回 7 结果。
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  • 作者: Daojun DiaoHu WangTangliang LiZhencan ShiXiaoqing JinTobias SperkaXudong ZhuMeimei ZhangFan YangYusheng CongLi ShenQimin ZhanJing YanZhangfa SongZhenyu Ju ( Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China;Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, China;Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, China;Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China;Zhejiang Hospital, Hangzhou, China;Leibniz Institute on Aging, Fritz Lipmann Institute (FLI), Jena, Germany;Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, China;Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, China;Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China;Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, China;Life Sciences Institute, Zhejiang University, Hangzhou, China;State Key Laboratory of Molecular Oncology and Cancer Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China;Zhejiang Hospital, Hangzhou, China;Department of Colorectal Surgery, Sir Run Run Shaw Hospital affiliated to Zhejiang University, Hangzhou, China;Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China;Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, China )
  • 出处: EMBO reports 2018 Vol.19 No.10
  • 关键词: epigenetics Gadd45a stem cell aging telomere 
  • 摘要: Progressive attrition of telomeres triggers DNA damage response and limits the regenerative capacity of adult stem cells during mammalian aging. Intr
  • 作者: Hao TangXiaolei ChengXiuqin FanCihang LiuDongxing ShaoBin JiangJunyue XingXiaotian ZhangXia YiWengong WangHao TangXian WangHu WangFan YangYusheng CongZhenyu JuHu WangYusheng CongZhenyu JuFan YangMengmeng ZhangJinbiao MaYanlian ChenYuyang TianZhou SongyangWenbin MaYong ZhaoYali DouMyriam Gorospe ( [1]Department of Biochemistry and Molecular Biology, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, School of Basic Medical Sciences, Peking University Health Science Center, 38 Xueyuan Road, Beijing, 100191, China;[2]Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University Health Science Center, 38 Xueyuan Road, Beijing, 100191, China;[3]Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, 510632, China;[4]Institute of Aging Research, Hangzhou Normal University, School of Medicine, Hangzhou, 311121, China;[5]Leibniz Institute for Age Research - Fritz Lipmann Institute, Friedrich-Schiller University of Jena, Jena, 07745, Germany;[6]Department of Biochemistry, School of life Sciences, Fudan University, 2005 Road Songhu, Shanghai, 200433, China;[7]Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510006, China;[8]Department of Pathology and Biological Chemistry, University of Michigan, 1301 Catherine Street, Ann Arbor, MI, 48105, USA;[9]Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, 251 Bayview Blvd., Baltimore, MD, 21224, USA )
  • 出处: Nature Communications 2018 Vol.2018 No.1
  • 摘要: Telomerase consists of the catalytic protein TERT and the RNA TERC. Mutations in TERC are linked to human diseases, but the underlying mechanisms are
  • 作者: Junzhi ZhouPeng XiQi ZhouDeqiang DingYusheng Cong ( Key Laboratory for Cell Proliferation and Regulation Biology of Ministry of Education, Institute of Cell Biology, College of Life Sciences, Beijing Normal University;Institute of Aging Research, Hangzhou Normal University School of Medicine )
  • 出处: 科学通报(英文版) 2014 P2324-2330 (发文年影响因子:0.8282)
  • 关键词: C53 hTERT Tumor suppressor Telomerase 
  • 摘要: Telomerase is a large ribonucleoprotein complex that contains a catalytic telomerase reverse transcriptase(TERT)and an RNA template.Telomerase activit
  • 被引量:4

  • 作者: 丛羽生 ( 杭州师范大学衰老研究所 )
  • 出处: 2014年衰老与转化医学研讨会暨第三届全国老年健康与转化医学论坛 2014 2014年衰老与转化医学研讨会暨第三届全国老年健康与转化医学论坛论文集
  • 会议录: 2014年衰老与转化医学研讨会暨第三届全国老年健康与转化医学论坛论文集
  • 关键词: 胞膜窖 衰老 
  • 作者: Junzhi Zhou Peng Xi Qi Zhou Deqiang Ding Yusheng Cong ( 1. Key Laboratory for Cell Proliferation and Regulation Biology of Ministry of Education, Institute of Cell Biology, College of Life Sciences, Beijing Normal University, Beijing, 100875, China 2. Institute of Aging Research, Hangzhou Normal University School of Medicine, Hangzhou, 311121, China )
  • 出处: Chinese Science Bulletin 2014 Vol.59 No.19 P2324-2330
  • 关键词: C53 hTERT Tumor suppressor Telomerase 
  • 摘要: Telomerase is a large ribonucleoprotein complex that contains a catalytic telomerase reverse transcriptase (TERT) and an RNA template. Telomerase acti
  • 作者: Zhiyang ChenWeiwei YiYohei MoritaHu WangYusheng CongJunping LiuZhicheng XiaoK.Lenhard RudolphTao ChengZhenyu Ju ( Institute of Aging Research,Leibniz Link Partner Group on Stem Cell Aging,Hangzhou Normal University School of Medicine,Hangzhou 310036,China;Leibniz Institute for Age Research-Fritz Lipmann Institute,Jena 07745,Germany;lnstitute of Aging Research,Leibniz Link Partner Group on Stem Cell Aging,Hangzhou Normal University School of Medicine,Hangzhou 310036,China;Leibniz Institute for Age Research-Fritz Lipmann Institute,Jena 07745,Germany;Department of Anatomy and Developmental Biology,Monash University,Clayton,Victoria 3800,Australia;State Key Laboratory of Experimental Hematology,Institute of Hematology,Chinese Academy of Medical Sciences and Peking Union Medical College,Tianjin 300020,China )
  • 出处: 2014天津国际干细胞论坛 2014
  • 作者: Yuyin LiGuojun PanYue ChenQian YangTiantian HaoLianbo ZhaoLong ZhaoYusheng CongAipo DiaoPeng Yu ( a School of Biotechnology, Tianjin University of Science and Technology, Key Lab of Industrial Fermentation Microbiology of the Ministry of Education, Tianjin, 300457, China b China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, Sino-French Joint Lab of Food Nutrition/Safety and Medicinal Chemistry, Tianjin University of Science and Technology, Tianjin 300457, China c Institute of Aging Research, Hangzhou Normal University, School of Medicine, Hangzhou, Zhejiang Province 311121, China )
  • 出处: European Journal of Medicinal Chemistry
  • 关键词: hTERT Inhibitor Apoptosis Synthesis 
  • 摘要: Telomerase is aberrantly expressed in many cancers and plays an important role in the development of cellular immortality and oncogenesis, which makes
  • 点击量:1

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  • 职称:教授
  • 研究方向: 衰老生物学、细胞生物学
  • 当前任职教学科研单位: 医学院 医学院
  • 邮箱: yushengcong@163.com
  • 电话: 18262223345
  • 丛羽生教授主要从事细胞衰老和无限增殖化分子机理研究。实验室总体目标是通过对细胞衰老及无限增殖化的分子机理、端粒酶生物学功能等基础分子细胞生物学研究,探索正常人体细胞从年轻到衰老以及癌变过程的分子生物学机制,为有效控制衰老、预防和治疗衰老相关疾病、探索肿瘤发生和发展的分子机理提供科学基础。
    【学习工作简历】 1981.9-1985.6 吉林农业大学农学专业,本科生 1987.9-1989.9 [法国] 斯特拉斯堡大学,硕士生 1989.9-1994.3 [法国]巴黎南大学/居里研究所,博士生 1995.2-1997.3 [美国]圣安东尼奥德州医学中心,博士后 1997.8-2001.2 [加拿大]麦克马斯特大学,博士后 2001.2-2002.11 [美国]德州西南医学中心研究员 2002.11-2004.3 [美国]康涅狄格大学蛋白组学中心研究员 2004.3-2005.8 [美国]路易斯维尔大学Assistant Professor 2005.8-2011.12 北京师范大学京师特聘教授 2006.3-2009.3细胞增殖与调控生物学教育部重点实验室主任,细胞所所长 2011.12-至今杭州师范大学医学院
    【学术成就荣誉】 在国际上有较高影响的杂志上发表学术论文40余篇。主持国家自然科学基金项目5项, 作为课题负责人或学术骨干参与科技部“973”,“863”项目4项。作为完成人之一获得2009年中华医学一等奖,2010年国家科学进步二等奖,2008年细胞生物学国家级精品课和2010年分子生物学国家级精品课。2012年入选杭州市海外高层次人才引进计划(“521”)杭州市特聘专家。
    【社会学术兼职】 北京细胞学学会理事 中国老年学学会衰老与抗衰老科学委员会理事 中国老年保健医学研究会老年健康与转化医学分会委员 中国生物物理学会膜与细胞生物物理专业委员会委员
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